There is no doubt that the use of CBD is on the rise. That is why you can see CBD products almost everywhere. The number of dispensaries selling CBD has also increased significantly. Before the legalization of the drug, most people knew smoking was the only way you could consume the compound. That is despite the fact that ancient Chinese would mix it in their tea to get a soothing effect. Soon after legalization, various ingestion methods came about, including vaporizing, which seems to be the trendiest.
Another thing is that most people who are yet to have an encounter with vaporizing often ask one question, does it make you high? Well, No. There are many ways that CBD vaping makes you feel, and giving you the psychoactive effect is not one of them. That is because CBD has less than 0.3% THC, and that is not enough to give you a high effect. But then, in some ways vaporizing CBD makes you feel better, this includes:
Anyone who uses rick simpson oil from Toronto will confirm that it can relieve anxiety and that feeling is fantastic. As soon as you vape CBD vape juice, the vapor goes to your lungs from where it will make its way to the bloodstream. While there, it works with neurotransmitters by attaching itself to CB1 receptors. The CB1 receptors are responsible for the alteration of serotonin signals. Keep in mind that your moods get affected whenever there is a low serotonin hormone in your system. By inhibiting the absorption of the serotonin hormone, CB1 receptors lead to an increase in serotonin. Once that happens, you find that your mood becomes positive, and that is how CBD vape juice makes you feel better.
CBD vape juice can alleviate chronic pain
If you know you are suffering from pain that is giving you sleepless nights, then you no longer need to agonize. That is because among the benefits of CBD vape juice is that it can help you feel better by alleviating your pain. When you vape CBD vape juice, it ends up binding itself on the endocannabinoid receptors. It then activates the brain to inhibit the production of the FAAH enzyme, which tends to break down anandamide. That means you will end up having fewer FAAH so your body will not utilize anandamide compound, which means you are not going to feel pain. That is how CBD vape juice can alleviate pain.
CBD vape juice can enable you to have a good sleep
There is nothing better than having a quality sleep at night. But what happens if you can’t get sleep for various reasons? Well, vaporizing CBD can help you have a night of quality sleep. Your body has multiple glands, and one of them is the pineal gland. The gland exists in the middle of the brain. Whenever night falls, the pineal gland increases its production of melatonin, thus making you sleep better. That is, however, not the case if you suffer from conditions like insomnia. But if you vape CBD vape juice, it is going to attach itself to the endocannabinoid system. It triggers the pineal gland to produce more melatonin, and so you will end up having adequate and quality sleep. For all CBD oil products requirements, one can surf the net for Canadian mail order cannabis licensed dispensaries offering doorstep delivery.
It can help with depression
Depression is among the many things that can affect you negatively and leave you feeling irritated, bored, and sometimes it causes withdrawal symptoms too. Vaporizing CBD can help you with the condition. Depression mostly occurs due to hormonal imbalance in the body. CBD can work to trigger the endocannabinoid system as well as the brain to balance the hormones. It also gives you a relaxed feeling, thus leaving you feeling better than before. It is among the many importance of vaporizing that a huge percentage of people enjoy daily.
The discomfort that inflammation brings about can be quite annoying. But luckily, it is among the things that vaping CBD can help you treat. CBD triggers the cannabinoid receptors to maintain the levels of prolactin hormones at an optimum point. That is how it can stop inflammation. Coupling that function with the fact that it is an active anti-oxidant, it can reduce the effects of inflammation. That means people suffering from medical conditions like Alzheimer’s, eczema, and Crohn’s syndrome, which results from inflammation, can benefit from vaping CBD vape juice.
Apart from making you feel better due to the above conditions that it can treat, vaping CBD vape juice is also becoming prevalent. It is because vaporizing is among the easiest ways to ingest CBD. That is because all you need to do is grab a vaporizer and start enjoying its benefits. The preparation process is also easy, and it can only take you a day to learn. Another reason for its popularity is that vape juices come in different flavors, including strawberry, kiwi, and blue raspberry, among others. You thus have an option to pick flavors that suit you and start enjoying CBD vape.
It also doesn’t harm your lungs. With a vaporizer, you inhale the vapor and not the smoke. You are thus going to find yourself enjoying every hit that you take. Lastly, CBD vaporizer delivers the above effects much faster than other methods of consuming CBD. Once the vapor reaches your system, it quickly enters the bloodstream. You thus start feeling better within a short period.
CBD vape juice is a lifesaver when it comes to making you feel better. The product has various compounds, amino acids, as well as minerals. It is also among the most active anti-oxidants. That is why it can help alleviate and treat the above conditions, thus making you feel great. You also don’t have to worry since it is easy to consume, and it also gets to work faster. Within a short time of consuming CBD vape juice, you are going to start feeling the effects kick in.
This is a story of a man who sought to bring purer, more affordable access to hemp and CBD being betrayed, run-around, and even wrongfully arrested while trying to do the right thing.
We’re about to walk you through a #Kentucky born #corruption in the industrial #hemp trade. Imagine making a major investment in which you dotted all of your I’s and crossed all of your T’s through education, law, regulation, and business practice only to have it stolen. The very people who helped you bring new business to their state turn on you. From the beginning to the end, this is the story of a man who sought to bring purer, more affordable access to hemp and CBD being betrayed, run-around, and even wrongfully arrested while trying to do the right thing.
After this financing round, gippro will continue to consolidate its existing business, accelerate product development iteration and sales channel building, and strengthen the vape marketing and promotion ability at home and abroad.
At the same time, the two sides signed a joint venture agreement to jointly establish a Japanese operating company, engaged in research and development of atomization technology for healthy raw materials such as Cannabidiol (CBD), as well as brand operation and sales of related electronic atomization products, thus opening up the global industrial strategic development of the industrial cannabis part.
In recent years, the fever of industrial cannabis has not decreased, and the process of legalization of industrial cannabis has been accelerating all over the world. Cannabinoid will be widely used in medical and consumer fields. Among them, CBD vaping oil is one of the most mature health scenarios for cannabinoid application.
gippro is an electronic cigarette brand founded in Tokyo, Japan. It has mature and advanced experience in electronic atomization technology and electronic consumer equipment and supply chain resources. It has closed 10 million RMB Angel financing round in July 2018.
Meilleure International is an international industrial group listed on the main board of the Hong Kong stock exchange market. Its business covers the fields of healthy life, health care and hemp health.
The joint venture is based on the application of atomization technology. It’s also based on the good prospects of CBD in the Japanese health market and excellent policy environment. Research, development, production and operation of an internationalized electronic atomization equipment brand with cannabinoid with its featured healthy raw material, is another important measure for the global distribution of cannabis by Meilleure Health.
Demetrix, a hemp technology company, has completed a $50 million A round of financing for cannabinoid biosynthesis. Tuatara Capital led the round, and seed round investor Horizons Ventures also participated.
Horizons Ventures, as Li Ka-shing’s personal investment agency, has invested in Facebook, Skype, and in recent years has bet on artificial meat, encrypted assets and other frontier areas, investing in Zoom, Impossible Food, Bakkt, Slack and other companies.
What’s Demetrix’s background, what’s its advantage, why is it favored by Li Ka-shing’s personal investment institutions and participated in investment twice?
Key Technologies: Cannabinoid Synthesis by Yeast
Demetrix’s most interesting technology is cannabinoid synthesis by yeast. This technology is very similar to beer fermentation, but it uses genetically modified yeast cells to ferment cannabinoid.
But Demetrix is not the sole producer of cannabinoid synthesized by yeast. Several companies are involved, such as CB Therapeutics and Hyasynth Bio, a Canadian startup, to enter the cannabinoid synthesis market, and Intrexon Corporation and Surterra Wellness to co-invest. InMed Pharmaceutical Co. is also actively engaged in the biosynthetic cannabinoid project to promote commercial production of fermented cannabinoid based on $100 million.
Demetrix’s advantage is that Demetrix can obtain the exclusive license of its founder Jay Keasling’s research team in Berkeley, which is its absolute competitive advantage.
Key person: Jay Keasling
Jay Keasling, founder of the company and professor of chemical engineering and bioengineering at the University of California, Berkeley, is currently focusing on the development of Engineering Chemistry and genetic tools within microorganisms and one of the most important authorities in synthetic biology.
On February 27, 2019, Nature published a research paper on the chemical synthesis of cannabinoids and their unnaturalanalogues in yeast by enzymes, namely Complete biosynthesis of cannabinoids and their unnaturalanaloguesin yeast. Using galactose as raw material, heterologous reconstruction of cannabinoids biosynthesis pathway was completed in Saccharomyces cerevisiae, including cannabis. Biosynthesis of terpenoid phenolic acid (CBGA), tetrahydrocannabinol (THCA), cannabinol (CBDA) and their derivatives. Professor Jay Keasling, Ph.D. Hou Luo Xiaozhou of the Institute of Quantitative Biological Sciences, University of California, Berkeley, is the co-author of the paper.
After the publication of the results, it aroused wide repercussions. Jay Keasling subsequently established Demetrix in California and was authorized from the University of California, Berkeley, to use yeast fermentation technology to produce cannabinoid.
Prospects are promising: the demand for cannabinoid from edible cannabinoid products, medicines and daily chemical products is rising
A variety of cannabinoids have been proved to be of great medical value. The report released by Grand View Research Inc, an international market research company, predicts that the global market value of cannabis for medical use will be as high as $55.8 billion by 2025. At present, THC and CBD are mainly used for medical applications and drug synthesis. There are 306 CBD clinical trials in major countries and organizations around the world. In the future, a large number of safe and stable cannabinoid raw materials will be needed for drug delivery to the market.
In addition, cannabinoid-based food and beverage has become one of the popular trends in North America, and BDS Analytics, a company that studies the cannabis market, has published a report on the edible market of cannabis, which shows that expenditure on cannabis edibility is expected to increase from $1.5 billion in 2018 to $4.1 billion by 2022.
Cannabis skin care is also one of the trends in the future. Jefferies analysts predict that in the next decade, CBD alone will be able to reach $25 billion in beauty products and will account for 15% of the skin care market.
On the other hand, cannabis ban has not been lifted worldwide. Planting and production are still under supervision. How to solve the legislative problems and shortage of raw materials, perhaps biosynthesis is a good way.
At present, there are more than 130 cannabinoids, of which only about five or six have been studied. The content of cannabinoids in hemp flowers and leaves is only 0.1%, 0.01%, or even 0.001%, so the cost of extraction can be as high as 100,000-350,000 US dollars per kilogram.
Cannabinoid synthesis by yeast will greatly reduce the cost of synthesis and expand cannabinoid production capacity. In February, when Jay Keasling’s team published their paper, yeast cannabinoid production was THC 8 mg/l and CBD less than 8 mg/l, but now the company’s production has increased by several orders of magnitude. Jeff Ubersax, chief executive of Demetrix, said the company would continue to expand production to 2,000 to 20,000 litres by 2020.
Is there any other correlation between Li Ka-shing’s two investments in Demetrix?
In September 2017, Jay Keasling collaborated with Shenzhen Advanced Institute to establish a laboratory of synthetic biology.
Following the release of the results of the Jay Keasling team in February this year, the Jay Keasling team signed an agreement with a domestic biotechnology enterprise in Shenzhen Advanced College. The two sides will invest tens of millions of dollars to establish a joint laboratory. As for which company, whether it cooperates with biosynthetic cannabinoids has not been disclosed, but is it Demetrix’s first opportunity to attract Li Ka-shing’s investment?
In addition, many Chinese researchers have participated in the research of cannabinoid synthesis.
If we are careful, we will find that besides this project, many Chinese enterprises and research institutes have participated in the research of synthetic cannabis project.
We have previously reported that ICC International tobacco Corp. has completed its $1.2 million strategic investment in Biotii Technologies Corp., a private biotechnology company in Boston, Massachusetts. Biotii is also a company that synthesizes cannabinoids genetically, and its news reveals that Biotii has established an important partnership with leading medical research institutions in China. The Biotii Leadership Team also includes a Chinese, labeled as a graduate student of Xiamen University and co-founder of a government-funded start-up company.
This also shows that China has entered the field of biosynthetic cannabinoid early and is expected to become a strong player in this field. Whether it can truly achieve commercial production depends not only on technology, but also on the legislative environment. At present, there is no clear statement about the synthesis of cannabinoid at home and abroad, and wait and see.
Like with medical marijuana, the wonderful world of CBD can be slightly overwhelming for a newbie and with the mainstream media going crazy for its health benefits, more and more companies are popping up selling a variety of different CBD products, such as CBD vape, the vape pen, capsules, CBD gummies, and other CBD edibles, CBD isolate, a CBD tincture or two, and even CBD dog treats. With so much information (and misinformation) flying around the Internet and through word of mouth, many of those who are curious about experiencing the benefits of nature’s miracle supplement are finding themselves confused about what to take and when.
So, in a bid to clarify things and debunk some myths about CBD, or cannabidiol oil, along with the potential effects and benefits of CBD, this guide will tell you everything you need to know about how to get started with buying CBD for the first time. Looking to buy CBD? Read on.
Not All CBD Oil Is Created Equal
The very first thing you need to understand in order to get started with making a CBD purchase is that not all oils will be effective and the effects of CBD will differ. The rise in popularity with regards to CBD products means that every day, new CBD companies are popping up left, right, and center and, unfortunately, many of them offer poor quality oils at extortionate prices. You should always look for the following criteria before making a decision about which brand to purchase.
Full spectrum CBD not isolate
Organic-, GMO-, and pesticide-free
CO2 extraction method for purity
Transparency with regards to ingredients and concentrate
Third-party lab tested
The company is willing to provide a lab report on request
Legal amount of THC
Buying a full spectrum oil means that you will also be able to enjoy all of the benefits from the whole plant and not just the isolated cannabinoid compound.
Don’t Be a Penny Pincher
Absolutely everyone loves a bargain in life and, most often, if someone knows they can get away with cutting corners to save money to buy CBD oil in tincture form, they will! This is absolutely fine when it comes to superficial products, but not when it comes to a product that we ingest into our bodies. Trying to save money by buying CBD oil that is way cheaper than other brands is pretty much the same as setting fire to the total amount you will be paying. Producing a pure, full spectrum CBD oil that is extracted in the purest way is expensive, which is why many of the reputable CBD manufacturers charge a higher price for their products. If you purchase premium quality oil from a reputable vendor, you might pay a higher price, but you will also be safe in the knowledge that the positive benefits are in sight.
One Size Doesn’t Fit All
Each and every one of us has a completely unique endocannabinoid system and the efficacy of a particular dose of CBD depends on the following factors:
Severity of your condition
This means that two drops of CBD oil might work really well for some people, but won’t even touch the sides with others. As it stands, the dosage is one of the biggest hurdles that cause new CBD users to become frustrated or give up in favor of pharmaceuticals. Before purchasing CBD oil, consider how serious your symptoms are and how you usually respond to medication. If you usually need a higher dose to feel an effect, then you might need to gradually increase your dose of CBD to several drops each day, in which case buying a bigger sized bottle could end up saving you money in the long run.
Do Your Research
And, by that, we mean Google should become your best friend until you make a decision about which CBD oil to purchase. A simple search of “most reputable CBD companies in your area” should produce a list of rated and reviewed companies. And the great thing about the Internet is that you cannot hide from it. This means that a genuine company will have received reputable reviews and a company offering poor products will also be ousted. A good quality CBD brand will have received media praise as well as recommendations from users online.
If in Doubt, Ask!
2019 has seen a rise in small businesses, especially within the CBD industry. Many of the companies offering CBD oil online will happily take the time to clear up any questions you might have and the better websites will offer an in-depth FAQ section.
Check the THC Levels
One of the common myths about CBD oil is that it will get you high. This is categorically not true and here’s why:
The Cannabis or hemp plant is made up of hundreds of compounds, the two primary ones being CBD and THC. THC is the compound that gets you high and it is only found in incredibly limited quantities in full spectrum oil. Legally, there cannot be more than 0.3% THC in CBD oil and this tiny amount will not produce any psychoactive effects when combined with CBD. If you live in a state where marijuana has been legalized, then it is possible that some dispensaries will sell oils containing a higher amount of THC. If in doubt, always check before making a purchase and, in any case, this information should be prominent on the packing of the product you want to buy.
The power of word of mouth goes a long way, especially when it comes to “hot topics” like CBD. Thanks to the Internet and public forums, scam artists are quickly exposed. In turn, good products will receive praise from consumers, media outlets, and, of course, social media. Spending some time browsing the Internet for CBD oil recommendations makes navigating the confusion you might be experiencing much easier and on finding a brand you feel confident about, a quick Google search on their company name will reveal everything you need to know about their products.
This article is originally published at SundayScaries.
The global industrial cannabis market has witnessed new growth since Canada legalized cannabis and the United States passed the Hemp Farming Act of 2018.
According to data released by Viridian Capital Advisors, a consulting firm in the hemp industry, global cannabis companies have raised nearly $13.8 billion in 2018. The industrial hemp part in the world’s major stock markets soars, and the continuous rise of the cannabis index becomes common.
Moreover, with the rapid increase of CBD users, CBD products get popular in the consumer market. It seems that more and more enterprises begin to invest and strengthen themselves in the CBD market.
CBD market potential is great according to the change of the giant enterprises
According to the Associated Press, Altria Group, the world’s largest tobacco company, bought 45% of Cronos Group, a well-known Canadian cannabis listed company, with $1.8 billion, and they might increase its stake to 55% in the next five years.
The food and beverage giants, such as Coca-Cola, Heineken, Budweiser and Constellation Group have also made great efforts to develop the CBD market and developed many foods and beverages containing CBD in 2018. According to various sources compiled by Canadian media BNN Bloomberg Television, Coca-Cola is very interested in developing beverages containing CBD ingredients.
Coca-Cola admits that they develop hemp drinks because CBD cola can relieve inflammation, pain and spasm. In response to media emails, the company also explained, “We are paying close attention to the growth of non-psychoactive CBD as a component of functional health drinks worldwide. This field is developing rapidly.
In addition, according to the Washington Times, senior executives of retail giants such as Walmart and Target have recently met quietly with manufacturers of beverages, fudge, topical creams and CBD oils.
In fact, this is not the first time Walmart was reported to set foot in the cannabis field. In October last year, Walmart’s Canadian company announced that it was exploring the possibility of selling CBD-containing products in stores in Canada. Although Wal-Mart spokesman Diane Medeiros said they would not sell any CBD products until full legalization, it continued to drive up Walmart’s share price after the news of the day.
Since then, Wal-Mart has announced a partnership with New Age Beverages Corporation, a health functional beverage company, to sell its three new beverage combinations in all retail stores in the United States.
Although Walmart repeatedly emphasized that the three products on sale would not involve CBD components, investors and the market remained optimistic, and the industry also said that the cooperation with New Age Beverage Company at this time might be the preparation for Walmart’s CBD products to be listed in the future.
Due to the huge medical value and market space of CBD products, senior consultants of ARCVIEW Group have evaluated CBD industry, and the market size of CBD is expected to reach 22 billion US dollars by 2022.
According to market research firm ARCVIEW, legitimate cannabis sales in North America reached about $7 billion in 2016, and sales are expected to grow at an average annual rate of 27% over the next five years, reaching $22.6 billion by 2021.
Koicbd of CBDJAPAN is a professional Japanese company that has 30 years exporting experience, and able to ship the CBD products to Hong Kong, Shenzhen, USA – Proved by Vapehk.
Growing CBD demand promotes Chinese CBD device manufacturing growth
On the other hand, industrial cannabis may still be a sensitive topic in the world, but with the introduction of many studies, not only the food retail giants and investors are optimistic about the development prospects of the industry, but also the manufacturing of CBD device will be boosted.
Compared with the traditional “flower” and “paste”, CBD oil is not only simpler and more convenient to use, but also can achieve the same effect. Because of this reason, the demand for CBD device in Europe and America has increased greatly, and China domestic suppliers of CBD atomization products & vapes have been actively sought.
We contacted CBD-related enterprise VELXtech recently, which is founded in Xixiang, Shenzhen in August 2018, is an innovative atomization technology solution supplier integrating strong technical foundation, high-end factory, perfect production system and quality control system, providing innovative, safe and effective atomization technology, device and related solutions for overseas CBD legal areas.
VELX tells us that the main reason why CBD device can develop at a high speed is that CBD not only has been proved to have an effective therapeutic effect on spasm, anxiety, inflammation and pain in a certain range of quantities, but also has an explosively growing user group with the demand increasing day by day“.
VELX, as early as its inception, took innovative CBD atomization technology development as the main direction, and completed VELX atomization technology by independent research and development. Based on this technology, VELX also develop a variety of its own new technical products, such as atomizers, batteries, disposable atomizing device, pod systems, etc. Moreover, they provide customized OED, ODM services and CBD technology solutions to the growing European and American CBD market.
In fact, VELX is a subsidiary company of Geekvape. As the company has six supply chain subsidiaries, it has great advantages in production, research and manufacturing, so it is easier to control product details, information transmission, quality consistency and so on.
VELX has established a strong core team for the development of CBD market, including R&D experience leaders in atomization technology field for many years, sales leaders who are good at the management and service of large overseas customers and the operation of fo overseas projects, and design teams who have been awarded the German Red Dot Award and if Design Award.
VELX stressed that although the production of any type of CBD oil is prohibited in China, the future prospects are still good from the perspective of device development. After all, most of the core technology of CBD devices comes from the electronic cigarette. For enterprises with a deep foundation of electronic cigarette manufacturing, the legitimacy of CBD only means business transformation and increased opportunities to enter the market.
VELX atomization technology has been used in many of the company’s products, and VELX passed relevant tests after the introduction of California Heavy Metals Act on CBD device. On the other hand, VELX has also developed a highly adaptable Prism battery based on the characteristics of CBD oil to enable customers to have a better CBD experience.
Though the long development cycle of CBD device needs a lot of trial and error, VELX team has reached a considerable level in research and development. As long as customers feedback a specific issue, the company can quickly put forward improvement plans according to customer needs, and accurately grasp the needs in use to provide most accurate and useful technical services for customers.
VELX said, “Technology research and development and high quality production are the foundation of VELX. On this basis, we will develop new products, technologies and other products related to this field, and become a trustworthy brand of CBD innovative atomization technology in the cannabis industry.”
Since the end of 2018, the United States passed the Agricultural Amendment Act, which removed industrial cannabis from the Controlled Substances Act, CBD industry has witnessed an unprecedented wave of growth. However, with the rising trend slowdown of traditional retail sales, the retail market has been constantly impacted. Food enterprises have to solve the current dilemma and actively embrace the new consumer market.
Although retailers are less likely to make high profits from CBD, consumers have shown strong willingness to consume CBD products, no matter from CBD oil, CBD device, functional drinks or other related categories. And there is a demand, there is a market. If there is no future for CBD development, VELX will not rush into the CBD field.
In addition, according to the financial report of Canadian cannabis producer Tilray for the first quarter of 2019, its revenue in the first quarter of 2019 was $23 million, rising nearly 195% compared to the same period last year. This shows that the growth momentum of CBD has not slowed down, and the action of the relevant enterprises to enter the CBD market is after good consideration and preparation.
Compare to the new brand VELX, ALD GROUP has been the number 1 for over 10 years in the CBD device manufacturing industry. And the invisible king of the CBD deviceshould be titled to ALD without any doubt. Click below to see more about ALD:
Mr. Tan Wei, the founder of HMI Group, is interviewed by the Chinese vape trend culture magazine Dr. V and published forward-looking opinions on the concept of industrial marijuana, and views on the present and future of the cannabis industry and the trend of the combination of vapes and marijuana.
“CBD is synonymous with health. The wave of global legalization of cannabis is due to the strong effects of cannabis on human health, especially for neurological diseases. Medical marijuana fully reflects people’s pursuit of physical health. This is something that no organization or government can block.”
Background: Selling recreation use cannabis to people in China is very likely to be sentenced to death
The following is the original interview:
Dr. V: “You have done a very large legal cannabis business in China. So what is the legalization of industrial marijuana?”
Tan Xin: “In traditional education, we began to hate drugs because of the opium war against the Chinese people. The attitude towards drugs is actually the same in the world. But everyone seems to have overlooked a problem, that is, the use and dosage, if properly controlled, many so-called poison ingredients can also become a good medicine.
For example, arsenic trioxide, also known as ‘arsenic’, has special effects in the treatment of certain leukemias. This shows that in a reasonable place, mineral poisoning can also be very good medicine.
The same is true for morphine, which is a form of opioid, but patients with advanced cancer use morphine to relieve pain. When morphine is used as a medicine, it gains world recognition. Morphine drugs are also known as opioids in the United States. In the recent ‘Fentanini Incident’, Trump has said that opioid products are poisoning Americans (such drugs are mostly produced in Chinese factories) because the drugs are addictive. But at the same time, the stock price of the companies involved in the production and sales of cannabisdiol (CBD) has risen sharply. This shows that in the future, cannabidiol will replace traditional morphine pain killer drugs.
The third example is Yunnan Baiyao, which is familiar to all of us. There is a Chinese medicine called Yunnan Uygur in the formula of Yunnan Baiyao. It is the ‘breaking grass’ mentioned in our martial arts novels and is toxic. Yunnan Baiyao was removed from Hong Kong in the past few years. Europeans and Americans have never agreed with this ingredient. However, the Chinese believe that the legal preparation process and legal use will bring benefits to the human body. Just like in ancient China, people have used poison to kill the poison.
We can say that marijuana is a useful ingredient as long as it is established as a starting point for the sake of health after talking about the above three cases. And it’s beneficial when using at a proper dose.”
Dr. V: What is your understanding of medical marijuana? What is the prospect of HMI in this regard?
Tan Xin: Pharmaceutical is the most healthy and ideal direction. Cannabis has more toxins than other plants. For example, poppies are difficult to make fast-consuming products and beverages, because a little use will immediately activate the human spirit, so it can only drugs can be used. Because of its complex composition, marijuana has more than one hundred ingredients that are not found in other plants. Many substances extracted from hemp is isolated from toxins can be used as food health products. Therefore, we cannot use the term “marijuana” to cover all the characteristics of marijuana.
Dr. V: What are the specific differences between recreational marijuana and industrialized marijuana? Does it mean that entertaining marijuana is cannabis that retains some toxins? Is medical marijuana that removes toxins and only retains health-care substances?
Tan Xin: It can’t be fully understood like this. Because the “toxin” component of cannabis, a “toxin” component, also has medicinal value, it is also a raw material for pharmaceuticals in biopharmaceuticals. However, if this ingredient is not used in medicine, it can become a major component of entertainment cannabis in the market.
CBD with Infinite Potential
Dr. V: As far as you know, what is the competitive advantage of the CBD in the legalization of cannabis worldwide?
Tan Xin: Cannabidiol is not legally available worldwide. Some countries are still relatively in the gray area. The latest news is that the regular session of the sixty-second session of the UN Commission on Narcotic Drugs will be held in Vienna from March 18 to 22, 2019. The cannabis industry is looking forward to the resolutions of the conference, as this meeting received and considered the following recommendations from WHO: Pure cannabinol (CBD) should not be included in the international drug control conventions, it is legal worldwide since this day. The application of CBD is quite extensive. I have seen reports that 7 out of 100 people in the United States will use related products, and the usage rate is very high, far exceeding THC. In the electronic cigarette industry, THC cigarettes have a market advantage in the early days of opening, but in reality, the potential of THC is limited. In the United States or Canada, people who smoke marijuana usually have a party, and some people may only smoke it one or two times in their lifetime. It is not a standing fast-consumer product. The CBD e-cigarette can be turned into a product that can be vaped at any time. It can relieve stress and so on, and it will be more competitive in the future.
Dr. V: How do you think about the legalization of CBD in China?
Tan Xin: There’s a future from the beginning. Everything has a breakthrough. Now that China has a breakthrough in “industrial use” of cannabis, we will develop it in a formal and state-prescribed form and gradually expand its influence. Whether through the way of atomization or eating, people should be able to enjoy the benefits of CBD.
Dr. V: We already know that many domestic enterprises have obtained industrial marijuana licenses. What do you think is the core of CBD in the future?
Tan Xin: I think these companies belong to those who see the potential of the future in the capital market, but can these new companies stick to it? First of all, we need to know what licenses are. Planting licenses are totally different from industrial hemp mosaic processing licenses. Planting licenses without subsequent extraction and processing capabilities are not of great value, so many planting enterprises must rely on extraction and separation enterprises to develop, and it is difficult for them to have core competitiveness in the industrial hemp industry.
Dr. V: As a listed company with permission to grow cannabis, what do you know about Shunhao Co., Ltd?
Tan Xin: Shunhao is one of the partners of Hanma Investment Group. The electronic cigarette company jointly owned by Shun Hao and Dongfeng is called Lvxin. A joint venture company was established with Hanma Group’s Hansu Biology, an extraction plant with the Industrial Hemp Mosaic Processing License, to explore the application of industrial hemp substrates in HNB vape products.
Dr. V: PAX, JUUL, PMI and other enterprises are involved in the CBD industry. What are your views on the global CBD industry future prospect?
Tan Xin: I don’t think the industry data of this industry is real enough. Every time an industry report comes out, it will be overturned by other industry reports in a month or two, and the number of reports is extremely large. I can not use a single data to summarize the future CBD market usage, but I can give an example of Hanma Group. We produce a drug for epilepsy, 300 mg per person per day, then 10,000 people will use one ton per year. In the future, if 5% of China’s 9 million epilepsy patients use our medicine, it will be 45 tons of CBD. China currently has 300 million smokers, so it would be a gigantic number for CBD usage.
CBD and Electronic Cigarette
Dr. V: At present, CBD has been integrated with electronic cigarette industry in North America, and electronic cigarette has become a derivative of cannabis. What do you think of this problem?
Tan Xin: If CBD is used in electronic cigarettes, it really changes the traditional entertainment scenario and use of electronic cigarettes. Therefore, making CBD electronic cigarettes needs later market education. In fact, electronic cigarette does not belong to cagarette in my opinion, but is an aerosol route of drug administration. We know that many asthmatic patients use aerosol route because of faster absorption. CBD electronic cigarettes are easy to understand if we change our concept into an atomized route of administration. But it can’t be the form of cigarette, which is also the idea I advocate with many electronic cigarette companies. Atomization platform is the concept of health, just like your magazine’s original intention is to focus on big health. In fact, the same thing can be said differently, and it will be more accurate for people. Therefore, the combination of electronic cigarette and marijuana cannot leave the word “health”, so that the application of industrial marijuana will have a stronger vitality.
Dr. V: Do you think that the combination of CBD and electronic cigarette equipment will become the best way of CBD intake and the industry trend?
Tan Xin: Some people have said that cannabis products will be the world’s largest consumer goods. In combination with marijuana, we can adjust the vapes to allow people to vape until there is a fantastic feeling. More marijuana consumers do not actually want to enjoy the overwhelming pleasure, just like many people drink but not to get drunk, they enjoy a slightly drunk feeling. Electronic cigarettes have the ability to make you little drunk, it can be controlled, so that the market space will be very large. From the perspective of investment of Altria and Anglo-American tobacco, the CBD industry is very promising.
Dr. V: How does a small electronic cigarette device realize the medical effect of CBD through atomization?
Tan Xin: If the electronic cigarette itself is added to the CBD, no matter what oil is used as the carrier, there is a problem of solubility, so it does not work well. Most electronic atomization device is also a conceptual product. For example, a 1-2 mg CBD does not have much impact on the human body. In the biopharmaceutical field, the CBD needs to achieve a certain amount of efficacy. The development of higher-end devices capable of heating pure CBD will have market space in the future. Our group is also doing this work, it will be more targeted at people with diseases that need treatment, not just a concept.
Dr. V: In the export of the vape industry, CBD has become one of the main raw materials of vape juice containing nicotine. Do you think China is likely to become an exporter of raw materials in the future?
Tan Xin: China’s not going to be the biggest exporter. Because with 40 years of development, China has no production advantage now. Our labor costs are very high. Countries like Vietnam and Myanmar have greater advantages. We need to make our own market now.
HMI, Present and Future of Industrial Cannabis in China
Dr. V: What are the main businesses of Hanma Investment Group at present?
Tan Xin: Hanma Group is the only enterprise with the whole cannabis industrial chain in China. From seed planting, extraction, processing, R&D, intellectual property rights, to products and markets, we have formed an industrial closed-loop. Hanma Group has done so many things from beginning to end, which is not my wish, because China’s law is not sound at the beginning, no company can cooperate with us, to make the industrial chain is also a special case of the times. From the first day of participating in the industry of cannabis, we have positioned the investment group in the direction of biopharmaceuticals, and its strategic direction is very clear.
For some non-pharmaceutical patents and research results, we will also slowly release to integrate with the fast-food industry. At present, ALD, who has worked as our partner, has the main direction of marijuana oil vape product. Some large domestic electronic cigarette companies are also buying products from us to do research. A listed company providing flavor for China tobacco is also developing and heat not burn cigarettes with our raw materials.
In addition to the tobacco fast consumer industry, we have also made some cooperation with some food brands to make cannabis food, of course, in accordance with Chinese law. We have plans to do research and development with some big cosmetics companies. Cannabis catechol is the raw material of some skin care products in Europe and America. It has good effects on anti-aging, whitening, acne removal and cell regeneration.
Hanma Investment Group concentrates on one thing. We are more focused on the research and development of upstream, midstream and application technology of industrial hemp. It is not the advantage of Hanma Group to push a variety of fast consumables to the terminal retail market. We will find some companies that are able to and willing to differentiate and upgrade, and use the channel advantages of their traditional industries to develop together.
In China, marijuana in the form of entertainment is problematic and prohibited. As a Chinese enterprise, Hanma Group opposes the legalization of all forms of entertainment marijuana. We only pursue its industrial and medicinal uses. We will also widely promote the use of fast-consuming products. We will never touch entertainment marijuana.
Dr. V: What is the global industrial prospect of Hanma Investment Group now? What kind of plan will HMI carry out in the future?
Tan Xin: We don’t invest in recreational marijuana. There’s no capital market for recreational marijuana. It belongs to some special countries and regions, and industrial marijuana belongs to the whole world. We have set up a factory in Nevada and obtained a full license for industrial marijuana. We plan to start production in the second half of this year. Hanma Group will also get a license in Canada this year to improve the development in North America. Relying on Canadian federal cannabis law, American federal industrial cannabis law, and Chinese industrial cannabis law, Hanma Group accounts for almost one-third of the world’s most cannabis consumable market, with a population of about 17.8 billion, which is our first step in the plan.
The second step is in Europe. For example, in Germany and Britain, the grow of vapes is also very fast, so our strategic direction will be developing there and promote products.
Dr. V: We noticed that you also used iQOS’s heat not burn product. Do you have any feelings or suggestions about this product after using it?
Tan Xin: I’m also designing a product that specializes in hemp heat not burn. Heating cannabis without burning is also the preferred direction of tobacco giants in the world. Now we can see how much tar is on the packages of cigarettes. Our products are made from cannabis leaves. It can also clearly indicate the content of CBD and THC, or only contain CBD. This requires classification and superb technology. Industrializing agricultural products like marijuana can complete what I said. Firstly, all the ingredients of hemp should be separated and then reassembled to make this kind of tobacco. This is much more complicated than the ordinary vapes, but the experience will be more than the ordinary vapes. Large international tobacco companies have visited our factories and are hopeful to cooperate with Hanma Investment Group, because only we have the technology and ability to separate and restructure agricultural products. This product will be more competitive in the future market.
At the end of the interview, Tan Xin told Dr. V’s readers: “I hope the development of the cannabis industry, the application of cannabis bisphenol, in the field of electronic cigarettes, is not only a process for us to enjoy entertainment, but also to enjoy health.” This is the hope for every vapor, and also a good vision for the combination of vapes with the CBD industry.
With the medical efficacy of CBD (or cannabisdiol) being confirmed, a wave of “legalization of industrial marijuana” has been launched around the world, and e-cigarette has become one of the easiest and most enjoyable ways to use CBD in Europe and America.
Although the use of CBD through e-cigarettes has been shown to provide users with more biological activity than the “edible” or “oral” approach (the user can absorb more CBD), since the CBD does not have any “Excited” function, why can it become the mainstream product of emerging consumption in overseas markets?
At present, there are a large number of research opinions around the world to support the positive effects of CBD on various diseases and symptoms. In this article, Vape hk will present the research records and benefits of using the CBD.
CBD is a compound found in cannabis plants that can be extracted from cannabis or industrial cannabis and processed into food, medicine or vape juice for electronic cigarettes.
The most common effects of CBD are “relaxation”, “the alleviation of pain”, “the alleviation of anxiety” and “improvement of emotions”. According to a study conducted in mice, CBDs can cause fatigue or lethargy at higher doses, but at small doses, they can produce the opposite effect of alertness.
When using CBD vape oil, you will feel a more pronounced response than using an oral spray or food. The following are the most common effects associated with CBD oil:
● Relax and comfort
● relieve pain
● Reduce anxiety
● Emotional improvement
● sleepiness (high dose) / alertness (low dose)
CBD research and medical value
CBD does not have the psychoactive effect of THC, and its medical value is very high. Many studies have confirmed that CBD is used for different symptoms, and has pharmacological effects such as antispasmodic, anti-anxiety, anti-inflammatory and pain relief.
Brazilian studies in 1973 showed that the CBD actively reduced or prevented convulsions in rodents. This was confirmed by another study conducted a year later, which showed that epilepsy patients who received 200 to 300 mg of CBD per day had fewer seizures.
One of the most well-documented examples is that a young girl named Charlotte Figi suffers from Dravet’s syndrome (severe myoclonus epilepsy), a rare disease with a common drug treatment. She then received a very special drug treatment called the CBD strain called Charlotte’s Web. At present, Charlotte lives a healthy life, her seizures are greatly reduced from about 300 times a week to two or three times a month.
In June 2018, the US Food and Drug Administration approved the launch of the Epidiolex product, a CBD drug used to treat patients with epilepsy 2 years of age and older. Epidiolex was the first FDA-approved CBD drug, and the drug significantly reduced the frequency of seizures in a study of double-blind in 120 subjects (both testers and subjects were not aware of the trial).
One of the most common effects of CBD is mild sleepiness, especially when used at higher doses. A study conducted in the 1970s reported the sleep-inducing effect of CBD in rodents.
In people with insomnia, it has been shown that taking CBD at a dose of about 160 mg increases sleep time. In non-insomnia patients, a similar effect was observed at high doses approaching 600 mg. In the case of microdoses, it has been studied that CBD can promote alertness rather than cause lethargy.
A number of studies have been conducted to show that CBD can effectively treat anxiety disorders. Studies using magnetic resonance imaging and single photon emission computed tomography have confirmed the anxiolytic effects of CBD on the brain. In addition, according to a study conducted on rats, the mood regulation of CBD can also be used to treat depression. The researchers believe that CBD may treat other forms of anxiety disorders such as obsessive-compulsive disorder and post-traumatic stress disorder.
4. Mental illness
A study in 1982 showed that CBD can suppress symptoms associated with mental illness. It has been observed that patients in South African psychiatric hospitals have reduced frequent episodes of psychosis when treated with low levels of CBD. There are also studies showing that even in healthy individuals, CBD can help reduce the symptoms of psychosis.
In 1995, a case study showed that CBD is also a safe and effective alternative to schizophrenia. This has led researchers to believe that the CBD can help reduce the impact of mental illness.
5. Heart disease
Further research on the antioxidant and anti-inflammatory properties of CBD suggests that it can prevent damage from cerebral ischemia, a heart disease that can cause stroke. Other studies on rodents have also demonstrated significant cardioprotective properties of CBD.
The anti-inflammatory effects of CBD have led scientists to believe that it can be used as a treatment for type 1 diabetes. There are also studies on “diabetes in mice with diabetes after improvement in the use of CBD.” In addition, recent surveys have observed the effect of CBD on attenuating high glucose.
ISA Science CEO Mark J. Rosenfeld M.S., P.h.D said: “CBD is different from other existing diabetes drugs, and the CBD may actually inhibit, reverse and cure the disease.”
7. Side effects of chemotherapy
Symptoms of nausea and vomiting after chemotherapy are actually the primary treatment targets in early CBD clinical trials. By 1990, a survey showed that more than 44% of members of the American Society of Clinical Oncology recommended the use of CBD for at least one chemotherapy patient, as studies in rats have shown the notion that CBD is equally effective in treating these symptoms.
8. Antioxidant and neuroprotective effects
A study in the late 1990s pointed out how CBD reduces hydroxide-induced oxidative damage, which means that CBD is an effective antioxidant and neuroprotective agent. Other studies that have been performed have also shown that CBD may have therapeutic potential for Alzheimer’s disease and Parkinson’s disease.
9. Anti-inflammatory effects
Several reports have shown the anti-inflammatory effects of CBD in mouse experiments. The data emphasizes that CBD can be an effective treatment for arthritis due to its immunosuppressive and anti-inflammatory effects. It has also been found to be effective in treating contraction of the sciatic nerve.
Last year, many NBA stars entered the CBD industry, hoping that the NBA would agree to use the CBD as a substitute for traditional painkillers to reduce the sequelae of athletes after taking painkillers.
In summary, although the two brothers, CBD and THC, are the same roots, they have very different effects on the human body. As more and more countries legally and recognize the medical value of the CBD, coupled with the introduction of various disease treatment research, I believe that even if they are the same cannabis products, the public can make rational judgments.
Of course, even if the medical value of the CBD is higher, it is necessary to pay attention to the use restrictions according to the national conditions. In China, the CBD does not allow private import and manufacture, and only state-approved manufacturers can manufacture CBD related products. However, at present, domestic manufacturers do not have permission to produce CBD oil, so vaper should not accidentally touch the legal red line in order to use the CBD, resulting in irreparable regret in prison.